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FSCN1 (基因名), Fascin (蛋白名), FSCN1_HUMAN.
产品名称:

Human FSCN1/ Fascin ELISA Kit
聚束蛋白

货号:

E1757h

商标:
EIAab®
监管等级:
别名:

55 kDa actin-bundling protein, Singed-like protein, p55, FAN1, HSN, SNL

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.78-50ng/mL
灵敏度:
0.34ng/mL
特异性:
Natural and recombinant human Fascin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Human FSCN1 ELISA Kit
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Human FSCN1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤4.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤8.2%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

100

94-106

Plasma

102

96-108

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

88-97%

88-97%

101-111%

97-106%

EDTA plasma(n=5)

98-106%

93-102%

99-110%

108-116%

heparin plasma(n=5)

101-111%

 

101-111%

100-111%

103-113%

 

通用注释


亚单元:
Interacts with RUFY3 (via N-terminus); the interaction induces neuron axon development. Associates with beta-catenin (By similarity). Interacts with PLXNB3 (PubMed:21706053).


功能:
Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.


亚细胞位置:
Cytoplasm Cytosol Cytoplasm Cytoskeleton Cell projection Filopodium Cell projection Invadopodium Cell projection Microvillus Cell junction In glioma cells, partially colocalizes with F-actin stress fibers in the cytosol (PubMed:21706053). Colocalized with RUFY3 and F-actin at filipodia of the axonal growth cone. Colocalized with DBN1 and F-actin at the transitional domain of the axonal growth cone (By similarity).


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