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Dnm2 (基因名), Dynamin-2 (蛋白名), DYN2_MOUSE.
产品名称:

Mouse Dnm2/ Dynamin-2 ELISA Kit
发动蛋白2

货号:

E1164m

商标:
EIAab®
监管等级:
别名:

Dynamin UDNM, Dyn2

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
15.6-1000pg/mL
灵敏度:
7.92pg/mL
特异性:
Natural and recombinant mouse Dynamin-2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Mouse Dnm2 ELISA Kit
规格 & 价格: cart
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Mouse Dnm2 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with SHANK1, SHANK2 and NOSTRIN. Interacts with SNX9. Interacts with SNX33 (via SH3 domain). Interacts with MYO1E (via SH3 domain). Interacts with CTTN and ACTN1 (By similarity). Interacts with MYOF and SH3BP4 (PubMed:17702744, PubMed:16325581). Interacts with PSTPIP1. Interacts with CTNND2 (By similarity). May interact with PIK3C3 (PubMed:18425118). May be a component of a complex composed of RAB5A (in GDP-bound form), DYN2 and PIK3C3 (PubMed:18425118).


功能:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:18923138). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (PubMed:18425118).


亚细胞位置:
Cytoplasm Cytoplasm Cytoskeleton Cell junction Membrane Clathrin-coated pit Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell junction Synapse Midbody Cell projection Phagocytic cup Cytoplasmic vesicle Phagosome membrane Peripheral membrane protein Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones. Microtubule-associated. Also found in the postsynaptic density of neuronal cells (By similarity). Co-localizes with PIK3C3 and RAB5A to the nascent phagosome (PubMed:18425118).


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