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GRK2 (基因名), Beta-adrenergic receptor kinase 1 (蛋白名), ARBK1_HUMAN.
产品名称:

Human GRK2/ Beta-adrenergic receptor kinase 1 ELISA Kit

货号:

E15707h

商标:
EIAab®
监管等级:
别名:

G-protein coupled receptor kinase 2, Beta-ARK-1, ADRBK1, BARK, BARK1

检测方法:
ELISA
特异性:
Natural and recombinant human Beta-adrenergic receptor kinase 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human GRK2 ELISA Kit
规格 & 价格: cart
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Human GRK2 ELISA Kit
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通用注释


亚单元:
Interacts with GIT1 (By similarity). Interacts with, and phosphorylates chemokine-stimulated CCR5. Interacts with ARRB1. Interacts with LPAR1 and LPAR2. Interacts with RALA in response to LPAR1 activation. ADRBK1 and RALA mutually inhibit each other's binding to LPAR1.


功能:
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.


亚细胞位置:
Cytoplasm Cell membrane


该产品尚未在任何出版物中被引用。
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