KIRREL1 (基因名), Kin of IRRE-like protein 1 (蛋白名), kirr1_human.
产品名称:
Human KIRREL1/ Kin of IRRE-like protein 1 CLIA Kit
肾病样蛋白1
货号:
U2838h
商标:
EIAab®
监管等级:
别名:
Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, NEPH1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Kin of IRRE-like protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Development Biology
通用注释
亚单元:
Interacts with TJP1/ZO-1 and with NPHS2/podocin (via the C-terminus). Interacts with NPHS1/nephrin (via the Ig-like domains); this interaction is dependent on KIRREL1 glycosylation. Homodimer (via the Ig-like domains). Interacts when tyrosine-phosphorylated with GRB2 (By similarity).
功能:
Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity).
亚细胞位置:
Cell membrane
Single-pass type I membrane protein
Predominantly located at podocyte slit diaphragm.
该产品尚未在任何出版物中被引用。
反馈墙
评论数 : 0
所有用户
所有用户
默认排序
默认排序
最近
早期
目前还没有评论。
通知
规格
数量
单价 (¥)
小计 1 (¥)
小计 2:
¥
规格
数量
单价 (¥)