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KIRREL1 (基因名), Kin of IRRE-like protein 1 (蛋白名), kirr1_human.
产品名称:

Human KIRREL1/ Kin of IRRE-like protein 1 CLIA Kit
肾病样蛋白1

货号:

U2838h

商标:
EIAab®
监管等级:
别名:

Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, NEPH1

检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Kin of IRRE-like protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Development Biology
Human KIRREL1 CLIA Kit
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Human KIRREL1 CLIA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with TJP1/ZO-1 and with NPHS2/podocin (via the C-terminus). Interacts with NPHS1/nephrin (via the Ig-like domains); this interaction is dependent on KIRREL1 glycosylation. Homodimer (via the Ig-like domains). Interacts when tyrosine-phosphorylated with GRB2 (By similarity).


功能:
Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity).


亚细胞位置:
Cell membrane Single-pass type I membrane protein Predominantly located at podocyte slit diaphragm.


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