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Bmp2 (基因名), Bone morphogenetic protein 2 (蛋白名), bmp2_mouse.
产品名称:

Mouse Bmp2/ Bone morphogenetic protein 2 CLIA Kit
骨成型蛋白2

货号:

U0013m

商标:
EIAab®
监管等级:
别名:

Bone morphogenetic protein 2A, BMP-2A, BMP-2, Bmp-2

检测方法:
CLIA
实验类型:
Sandwich
检测范围:
7.8-500pg/mL
特异性:
Natural and recombinant mouse Bone morphogenetic protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Mouse Bmp2 CLIA Kit
规格 & 价格: cart
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Mouse Bmp2 CLIA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer; disulfide-linked (By similarity). Interacts with SOSTDC1, GREM2, RGMA, RGMB and RGMC. Interacts with ASPN. Interacts with MFAP5. Interacts with FBN1 (via N-terminal domain) and FBN2.


功能:
Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。
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