ACTB (基因名), Actin, cytoplasmic 1 (蛋白名), actb_human.
产品名称:
Human ACTB/ Actin, cytoplasmic 1 CLIA Kit
细胞质肌动蛋白1
货号:
U8725h
商标:
EIAab®
监管等级:
别名:
Beta-actin
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
0.195-12.5ng/mL
特异性:
Natural and recombinant human Actin, cytoplasmic 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Signal Transduction
通用注释
亚单元:
Interacts with CPNE1 (via VWFA domain) and CPNE4 (via VWFA domain) (By similarity). Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of KMT2E/MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCSAM. Interacts with TBC1D21.
功能:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
亚细胞位置:
Cytoplasm
Cytoskeleton
Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
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