A2ML1 (基因名), Alpha-2-macroglobulin-like protein 1 (蛋白名), A2ML1_HUMAN.
产品名称:
Human A2ML1/ Alpha-2-macroglobulin-like protein 1 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9, CPAMD9
检测方法:
CLIA
特异性:
Natural and recombinant human Alpha-2-macroglobulin-like protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Monomer.
功能:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity). Displays inhibitory activity against chymotrypsin, papain, thermolysin, subtilisin A and, to a lesser extent, elastase but not trypsin. May play an important role during desquamation by inhibiting extracellular proteases.
亚细胞位置:
Secreted
数据库链接
UniGene:
STRING:
KEGG:
MIM:
Pfam:
Uniprot:
验证序列:
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