With the continuous advancement of science and technology, the quality of life and longevity of human beings have been greatly improved and extended. However, human beings have not yet completely cracked the code of aging, and researchers have been looking for ways to prevent the aging process.

On 2 December in the latest issue of Nature’s cover paper, scientists at Harvard Medical School used gene therapy to ectopically express the three genes Oct4, Sox2, and Klf4, inducing reprogramming of ganglion cells, and successfully triggering mouse eyes. Mature nerve cells restored young epigenetic information and used this method to reverse glaucoma and age-related vision loss in older mice.

If this discovery is confirmed in further research, it may make a major breakthrough in age-related vision such as glaucoma, and the vision problems of the elderly will be greatly improved.